Healthcare · United States

Registered Nurse Salary in San Diego, CA

With a US$139,520 median, San Diego ranks 3rd of 21 observed United States metros for registered nurse pay. The national median is US$97,600, so San Diego carries a 43% premium.

Observed data:city percentiles from public labour-market sources for this exact role and metro.

Showing amounts in USD (USD default). FX as of Sun, 01 Nov 2026 00:02:31 +0000. Convert currencies

Average salary
US$139,520
gross / year
Est. take-home
US$117,301
~16% effective tax
Hourly equivalent
US$67.08
based on 2,080 hrs/yr
vs. the United States avg
+43%
above average

Gross salary figures come from public labour-market data. Take-home, rent, savings, and inflation adjustments are simplified models for research — not payroll, listings, or immigration advice. Methodology.

San Diego registered nurse salary: rankings and context

After a simplified 16% national tax estimate that is about US$9,800 a month, in a metro with a cost-of-living index of 100.

How San Diego compares with United States and CA

On a United States league table of 21 metros, San Diego comes 3rd. One place higher is San Francisco at US$186,610, one lower is Los Angeles at US$135,560, and San Jose tops the list.

Across CA, the 4 observed metros average US$169,600; San Diego is 18% below that and 3rd in the state. The others: Los Angeles (US$135,560), San Jose (US$216,740) and San Francisco (US$186,610).

What the San Diego median is worth after tax and rent

With a COL index of 100, there is little difference between headline pay and price-adjusted pay (US$139,500).

Its place holds after a cost-of-living adjustment — 3rd of 21 either way.

After a simplified 16% effective national income tax, the median nets about US$9,800 a month. A modeled 1-bedroom (US$1,650) takes 17% of that, leaving around US$6,280 after modeled living costs.

Other CA options for registered nurses

Los Angeles (also in CA) pays US$135,560, 3% less than San Diego; modeled monthly leftover is US$250 lower.

A registered nurse moving from San Diego to San Jose (also in CA) would see the median rise 55% to US$216,740, with US$4,890 more left over monthly in our model.

New York (similar cost level, COL 100) pays US$119,720, 14% less than San Diego; modeled monthly leftover is US$1,260 lower.

Other San Diego jobs compared with registered nurse

Of the 9 roles we track in San Diego, Registered Nurse is 3rd by median; the highest is Lawyer (US$178,220).

Closest neighbours in the San Diego list: Software Engineer at US$163,270 (+17%) and Data Scientist at US$130,990 (-6%).

Where San Diego stands for junior and senior registered nurses

Entry-level registered nurses fare better here (3rd of 21 at the 10th percentile, US$102,480) than senior ones (4th at the 90th, US$175,210).

For the top 10% of earners, San Jose leads with US$235,190 at the 90th percentile, +34% against San Diego.

How wide registered nurse pay runs in San Diego

From the 10th percentile (US$102,480) to the 90th (US$175,210) is only 1.7×, a narrower spread than many roles.

Registered Nurse pay in San Diego: US$102,480 to US$175,210

US$102,48010THUS$128,38025THUS$139,520MEDIANUS$169,92075THUS$175,21090TH
Estimated pay distribution — the curve peaks at the median and widens with the pay range.

More context: United States salary hub (economy, inflation, visas) · Registered Nurse pay across the United States · cost-of-living calculator

Compare Registered Nurse pay

See how a registered nurse stacks up against similar healthcare roles in the United States.

Registered Nurse salary in other United States cities

CityMedian
Los Angeles, CAUS$135,560/yr
Portland, ORUS$130,310/yr
Seattle, WAUS$128,260/yr
New York, NYUS$119,720/yr

Frequently asked questions

What do registered nurses earn in San Diego?
The observed median is US$139,520 a year (US$67 an hour at 2,080 hours), with the middle of the market between the 10th percentile of US$102,480 and the 90th of US$175,210.
Which United States city pays registered nurses the most?
On cash pay, San Jose (US$216,740). On price-adjusted pay, San Jose. San Diego is 3rd and 3rd respectively.
Does San Diego pay registered nurses more than the rest of CA?
No — 3rd of 4 CA metros, -18% against the in-state average of US$169,600.
What is a registered nurse's take-home pay in San Diego?
On the US$139,520 median, a simplified national tax estimate leaves about US$9,800 a month. A modeled 1-bedroom is US$1,650 (17% of take-home), and the single-adult model ends about US$6,280 ahead each month.
Is registered nurse a high-paying job in San Diego?
It ranks 3rd of 9 occupations with observed San Diego data. The top-paying tracked role is Lawyer at US$178,220.