Healthcare · United States

Registered Nurse Salary in San Francisco, CA

Only 1 of 21 observed United States metros pay registered nurses more than San Francisco, where the median is US$186,610. That is 91% above the United States national median of US$97,600.

Observed data:city percentiles from public labour-market sources for this exact role and metro.

Showing amounts in USD (USD default). FX as of Sun, 01 Nov 2026 00:02:31 +0000. Convert currencies

Average salary
US$186,610
gross / year
Est. take-home
US$153,090
~18% effective tax
Hourly equivalent
US$89.71
based on 2,080 hrs/yr
vs. the United States avg
+91%
above average

Gross salary figures come from public labour-market data. Take-home, rent, savings, and inflation adjustments are simplified models for research — not payroll, listings, or immigration advice. Methodology.

Registered Nurse pay in San Francisco, by the numbers

After a simplified 18% national tax estimate that is about US$12,800 a month, in a metro with a cost-of-living index of 100.

San Francisco vs the national and CA picture

San Jose leads at US$216,740, 16% above San Francisco, while Jacksonville sits at US$83,520. The neighbours in the ranking are San Jose and San Diego.

Across CA, the 4 observed metros average US$169,600; San Francisco is 10% above that and 2nd in the state. The others: Los Angeles (US$135,560), San Diego (US$139,520) and San Jose (US$216,740).

Cost of living and take-home in San Francisco

Price levels in San Francisco (index 100) neither inflate nor shrink the paycheck much; adjusted for costs it is worth about US$186,600.

Cash rank and buying-power rank match for San Francisco: 2nd of 21.

Take-home on the median comes to roughly US$12,800 monthly (18% effective tax in our simplified model). Rent for a modeled 1-bedroom is 13% of it, and the single-adult budget ends about US$9,260 in the black.

Other CA options for registered nurses

Los Angeles (also in CA) pays US$135,560, 27% less than San Francisco; modeled monthly leftover is US$3,230 lower.

A registered nurse moving from San Francisco to San Diego (also in CA) would see the median fall 25% to US$139,520, with US$2,980 less left over monthly in our model.

In New York — similar cost level, COL 100 — the median is US$119,720 (-36% vs San Francisco), and the modeled budget leaves US$4,240 less each month.

Where Registered Nurse ranks among San Francisco jobs

Lawyer is the best-paid tracked role in San Francisco at US$212,500; registered nurse comes 3rd of 9.

Closest neighbours in the San Francisco list: Software Engineer at US$186,640 (0%) and Data Scientist at US$170,110 (-9%).

Entry-level vs senior registered nurse pay in San Francisco

Entry and senior pay rank the same in San Francisco: 2nd of 21 at both the 10th and the 90th percentile.

For the top 10% of earners, San Jose leads with US$235,190 at the 90th percentile, +5% against San Francisco.

Spread between low and high registered nurse pay in San Francisco

From the 10th percentile (US$119,290) to the 90th (US$223,770) is only 1.9×, a narrower spread than many roles.

Registered Nurse pay in San Francisco: US$119,290 to US$223,770

US$119,29010THUS$137,12025THUS$186,610MEDIANUS$215,63075THUS$223,77090TH
Estimated pay distribution — the curve peaks at the median and widens with the pay range.

More context: United States salary hub (economy, inflation, visas) · Registered Nurse pay across the United States · cost-of-living calculator

Compare Registered Nurse pay

See how a registered nurse stacks up against similar healthcare roles in the United States.

Registered Nurse salary in other United States cities

CityMedian
San Jose, CAUS$216,740/yr
San Diego, CAUS$139,520/yr
Los Angeles, CAUS$135,560/yr
Portland, ORUS$130,310/yr

Frequently asked questions

What is the average registered nurse salary in San Francisco?
Typically US$186,610. Entry-level offers start near US$119,290 and senior ones reach US$223,770; per hour the median works out to US$90.
Which United States city pays registered nurses the most?
San Jose has the highest observed median at US$216,740, 16% above San Francisco, which ranks 2nd of 21. After adjusting for prices, San Jose leads.
Does San Francisco pay registered nurses more than the rest of CA?
Yes — 2nd of 4 CA metros, +10% against the in-state average of US$169,600.
Can a registered nurse in San Francisco save money on the median salary?
In our model, yes: US$12,800 take-home, US$1,650 modeled rent, and US$9,260 left after other modeled costs each month.
Is registered nurse a high-paying job in San Francisco?
It is number 3 of the 9 roles with San Francisco percentiles on this site; Lawyer is first (US$212,500).